Product Name: Chlorhexidine acetate
Synonyms: Chlorhexidine di(acetate); 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; Hibitane diacetate; Chlorhexidine di acetate; ; 2,2'-hexane-1,6-diylbis(1-{(E)-amino[(4-chlorophenyl)amino]methylidene}guanidine) acetate (1:2); Chlorhexidine diacetate
Molecular Formula: C22H30Cl2N10・2(C2H4O2);
Molecular Weight: 625.55
InChI: InChI=1/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)
CAS Registry Number: 56-95-1;206986-79-0
EINECS: 200-302-4;200-238-7
Melting point: 153-156℃
Water solubility: 1.9 g/100 mL (20℃)
Hazard Symbols: Xn:Harmful;
Risk Codes: R22:;R43:;
Safety Description: S36/37:;
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Appearance
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White or almost white crystalline powder
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Identification
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A.
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To match with Reference Standard.
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B.
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A deep red color
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C.
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Chlorhexidine mp 132℃~136℃
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D.
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Gives reaction of acetates
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Tests
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Chloroaniline
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Not more than 500ppm
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Related substances
(by HPLC)
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To match with Reference Standard
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Loss on drying
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Not more than 3.5%
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Sulfated ash
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Not more than 0.15%
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Assay
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1,1′-(Hexane-1,6-diyl)bis[5-(4-chlorphenyl) biguanide] diacetate, Content: 98.0 per cent ot 101.0 per cent (dried substance)
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Chlorhexidine solution is the antiseptic of choice for many veterinarians for disinfecting the navels of foals. Chlorhexidine solution is often used as an anti-bacterial cleansng agent in the treatment and prevention of acute and chronic otitis externa, which is an ear infection often accompanied with inflammation. It is used as an oral cleansing solution in cases of gum inflammation and periodontal disease. Chlorhexidine is also used in the treatment of skin conditions, such as hot spots or acute dermatitis.
Chlorhexidine solution scrub is used to clean the perineal area and vulva of mares prior to breeding and also in obstetrical procedures.
